Platt Lab Mission:

To fuse engineering, cell biology, and physiology to understand how cells sense, respond, and remodel their immediate mechanical and biochemical environments for repair and regeneration in health and disease, then to translate that knowledge to clinics domestically and internationally to address global health disparities.

Platt Lab wins at PrePARE Workshop

Graduate student, Meghan Ferrall-Fairbanks, and post-doc, Dayne West, both trainees in the Emergent Behavior of Integrated Cellular Systems (EBICS, an NSF Science and Technology Center, STC) Center were selected to attend the Paths Afforded by the Research Enterprise (PrePARE) Professional Development Workshop in Indianapolis, IN on August 7-12. During this week-long workshop, trainee representatives from all the NSF STCs were taught a wide range of important professional skills, including creating individualized development plans, communicating science in presentations and interviews, and dining interview etiquette, to succeed in both academic and industrial careers. In addition to these skills, participants formed multi-institutional interdisciplinary teams to write an NSF RFA proposal to address a grand challenge. On the last day of the workshop, the written proposals were reviewed and each team presented their proposal. Two of the six teams tied to win the Amazon gift card prize. Meghan and Dayne's teams were both selected as winners! Meghan's team proposed to develop a new biomaterial that can be used to protect against coastal erosion. Dayne's team proposed improvements to the reduce-reuse-recycle triangle, by making all plastics recyclable. Congratulations to them both!

Binbin Chen awarded prestigious Soros Fellowship!

Former Platt Lab student Binbin Chin, now completing an MD/PhD in Genetics at Stanford University was recently awarded the prestigious Soros Fellowship. Click the picture above to read the full pres release

New publication on endothelial cell signaling in strokes of children with sickle cell disease

Dr. Platt, Suhaas Anbazhakan, and Platt lab Alumnus Philip Keegan have published an article in Biological Chemistry on regulation of cathepsin K by shear stress and TNFa. These two factors were found to act through independent pathways that converge at the point of gene regulation. This work was done to understand how the biomechanical and biochemical environment in children with sickle cell disease lead to an increased risk of stroke. This is also Suhaas’s first paper!